Determination of limiting ionic mobilities and dissociation constants of some local anaesthtics
この論文をさがす
説明
The limiting ionic mobilities and thermodynamic acid dissociation constants were calculated from isotachophoretic experiments for the local anaesthetics procaine, tetracaine, lidocaine, trimecaine, bupivacaine, cinchocaine, diperodone, diocaine, cocaine, psicaine-neu, tropacocaine, amylocaine, beta-eucaine and leucinocaine. The pH values at which the local anaesthetics with very similar limiting ionic mobilities can be isotachophoretically separated were determined from simulated mobility curves. The measuring apparatus employed a high-frequency contactless conductivity detector.
収録刊行物
-
- Journal of Chromatography A
-
Journal of Chromatography A 596 265-270, 1992-04-01
Elsevier BV