Off‐Line Leukapheresis Using Leukofiltration for Active Ulcerative Colitis: A Case Report

DOI PubMed

Search this article

Description

<jats:p><jats:bold>Abstract:</jats:bold> The method of leukocytapheresis for ulcerative colitis (UC) by using extracorporeal circulation (on‐line system) has been reported. To perform leukocytapheresis, we have applied leukocyte elimination filters for blood transfusion to leukocytapheresis without using extracorporeal circulation (off‐line leukocytapheresis system). Four hundred milliliters of peripheral blood was collected and reinfused through a leukocyte elimination filter. This procedure was repeated 5 times, and up to 2,000 ml of peripheral blood was treated. This method has been applied once a week for 5 weeks. We applied the off‐line leukapheresis system to a 31‐year‐old male ulcerative colitis patient. As a result, the frequency of defecation and the dose of medicine were effectively decreased, and endoscopic finding was also improved. Because of the absence of complications observed with the on‐line system, the off‐line leukocytapheresis system that we have applied to the clinical patient is simple, safe, and useful.</jats:p>

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top