Prompt engineering of GPT-4 for chemical research: what can/cannot be done?

書誌事項

公開日
2023-10-09
資源種別
journal article
権利情報
  • http://creativecommons.org/licenses/by/4.0/
DOI
  • 10.1080/27660400.2023.2260300
  • 10.26434/chemrxiv-2023-s1x5p
  • 10.6084/m9.figshare.24270647.v1
  • 10.6084/m9.figshare.24270647
公開者
Informa UK Limited

説明

<jats:p>This paper evaluates the capabilities and limitations of the Generative Pre-trained Transformer 4 (GPT-4) in chemical research. Although GPT-4 exhibits remarkable proficiencies, it is evident that the quality of input data significantly affects its performance. We explore GPT-4's potential in chemical tasks, such as foundational chemistry knowledge, cheminformatics, data analysis, problem prediction, and proposal abilities. While the language model partially outperformed traditional methods, such as black-box optimization, it fell short against specialized algorithms, highlighting the need for their combined use. The paper shares the prompts given to GPT-4 and its responses, providing a resource for prompt engineering within the community, and concludes with a discussion on the future of chemical research using large language models.</jats:p>

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