Adhesion-based cell sorter with antibody-immobilized functionalized-parylene surface

説明

We report the development of a micro cell sorter for extraction of rare cells from a limited amount of sample. The separation principle is based on specific adhesion with the aid of surface-immobilized antibodies. Antibody-immobilized channel walls are fabricated with a versatile technique using functionalized parylene. Performance of the cell sorter is characterized through cell velocity measurements, in which deceleration of positive cells up to 60% is observed. Cell separation with a mixture containing positive and negative cells is also demonstrated.

収録刊行物

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