The effect of X-ray irradiation-induced hyposalivation on caries induction in SPF rats infected withStreptococcus mutans

DOI

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Description

The effects of X-ray irradiation to the salivary glands on the induction of dental caries and on the oral microflora were examined in specific pathogen-free Sprague-Dawley rats fed a sucrose diet and inoculated with a strain ofStreptococcus mutans. Hyposalivation was induced by irradiation of 35 Gy and dental caries was significantly enhanced in irradiated rats infected withS. mutans. Bacteriological examinations at the end of the experiment demonstrated that the recoveries of lactobacilli and staphylococci significantly increased in hyposalivated rats with 50 Gy of irradiation. However, the recovery of the strain ofS. mutans from hyposalivated rats were not significantly higher than that of non-irradiated rats. These findings suggest that some acidogenic microorganisms such as lactobacilli and staphylococci may have played some role in promoting dental caries.

Journal

  • Oral Radiology

    Oral Radiology 8 65-71, 1992-12-01

    Springer Science and Business Media LLC

Details 詳細情報について

  • CRID
    1872835442777876480
  • DOI
    10.1007/bf02347812
  • ISSN
    16139674
    09116028
  • Data Source
    • OpenAIRE

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