Distribution of pancreatic elastase and metalloproteinase in several species of fish

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Abstract 1. 1. By CM-cellulose column chromatography, fifteen elastase-like enzyme preparations were separated from the activated pancreatic extracts of the gummy shark, red stingray, rainbow trout, carp, eel, bluefin tuna, yellowtail, sea bass, and angler. 2. 2. These preparations were characterized by using specific substrates and inhibitors. 3. 3. Pancreatic elastases, which belong to the group of serine proteinases, were found to be present in all the fishes examined. 4. 4. Among the fishes examined, pancreatic metalloproteinases with elastase activity were demonstrated only in the bluefin tuna and yellowtail.

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