Integrated chemical process for green chemistry. One-pot synthesis of 3-substituted 5-(β-sulfonylvinyl)indoles by in situ generation of toxic vinyl sulfone

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説明

Integrated chemical processes where multi-step reactions are consolidated in one pot are effective for realizing a green chemical process. In situ generation followed by consumption of toxic intermediates which are formed in the process enables their complete isolation from the environment. This is so for a vinyl sulfone intermediate in the synthesis of 3-substituted 5-(β-sulfonylvinyl)indoles. The validity of this idea is further confirmed by successful one-pot operations on an automated synthesizer.

収録刊行物

  • Green Chemistry

    Green Chemistry 3 13-16, 2001-01-01

    Royal Society of Chemistry (RSC)

詳細情報 詳細情報について

  • CRID
    1873398392307365120
  • DOI
    10.1039/b005645f
  • ISSN
    14639270
    14639262
  • データソース種別
    • OpenAIRE

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