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Reentrant conformational transitions in DNA molecules complexed with cationic surfactant
Description
The authors have established the conditions for the dissociation formation of DNA-CTAB complexes in organic solvents of different polarity. Fluorescence microscopy and CD spectroscopy indicate that DNA-CTAB complexes dissociate into their initial components at intermediate concentrations of alcohol, while conserving the double-stranded structure of native DNA. A further increase in the alcohol concentration leads to restoration of the complex, which is soluble under these conditions, i.e. in low-polarity organic media. As a novel phenomenon on DNA-CTAB interacting system, the authors have found the alcohol-induced reentrant globule-coil-globule transition in T4DNA-CTAB complexes.
Journal
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- MHA'98. Proceedings of the 1998 International Symposium on Micromechatronics and Human Science. - Creation of New Industry - (Cat. No.98TH8388)
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MHA'98. Proceedings of the 1998 International Symposium on Micromechatronics and Human Science. - Creation of New Industry - (Cat. No.98TH8388) 213-215, 2002-11-27
IEEE
