Papers from the 4th Medical Microbiology Interdisciplinary Commission (MEMIC) Symposium, “Viable but nonculturable microorganisms and emerging infectious diseases”
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説明
If you don’t see any bacterial growth after cultivation under supposedly favorable conditions, there should be no cells from the beginning. This has been a basic concept of bacteriology since the last century. In 1985, Prof. Rita R. Colwell of the University of Maryland in the United States proposed the idea that there are cells which apparently have lost their culturability but actually retain their metabolic activities. Under certain conditions, those cells may start to grow. This is now widely known as the “viable but nonculturable (VNC)” phenomenon. This new idea forces us to reconsider the classical concept of bacterial culturability. It also greatly stimulates us to understand more details about the physiological states of these “apparently dead” cells. Until now, at least 36 bacterial species, especially pathogens, have been reported to fall into the VNC state. Many questions remain unanswered, however. What kinds of bacteria enter the VNC state, and under what kinds of conditions? What kinds of methods are available, and how should we define the physiological states of cells in the VNC state?
収録刊行物
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- Journal of Infection and Chemotherapy
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Journal of Infection and Chemotherapy 6 107-, 2000-01-01
Elsevier BV