Studies on the synthesis of chemotherapeutics. <b>I</b>. Synthesis of 1‐(2‐tetrahydrofuryl)‐5‐fluorouracil [ftorafur] (studies on the syntheses of heterocyclic compounds. Part 703)
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説明
<jats:title>Abstract</jats:title><jats:p>Synthesis of 1‐(2‐tetrahydrol'uryl)‐5‐fluorouracil [Ftorafur] (<jats:bold>1</jats:bold>) which is well known as an antitumor agent from 5‐fluorouracil (<jats:bold>2</jats:bold>) with 2‐alkoxytetrahydrofurans (4) is described. Among these reactions, the best yield was obtained by using 2‐<jats:italic>t</jats:italic>‐butoxytetrahydrofuran (4h).</jats:p>
収録刊行物
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- Journal of Heterocyclic Chemistry
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Journal of Heterocyclic Chemistry 14 473-475, 1977-05-01
Wiley