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Local stimulation to single cell on tissue-mimicking microfluidic device
Description
In this paper, we developed a novel device for the analysis of intracellular response to external stimulus in single-cell level with high-spatial resolution that simulates in vivo tissue micro-environment. We utilized multidirectional UV lithography technique to realize simple 3-dimentional fabrication of the tissue-mimicking device. Microchannel with an aperture at its sidewall was fabricated. Localized delivery of stimuli to single cell was demonstrated here.
Journal
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- TRANSDUCERS 2009 - 2009 International Solid-State Sensors, Actuators and Microsystems Conference
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TRANSDUCERS 2009 - 2009 International Solid-State Sensors, Actuators and Microsystems Conference 1257-1260, 2009-06-01
IEEE
