Cell-Laden Microfiber as Growth Factor Supplier
説明
This paper demonstrated that microfiber-shaped hydrogel-encapsulated cells could be co-cultured with the target cells without cell contamination for six days and that they enhanced proliferation and differentiation of the target cells as growth factor supplier. When cultured with alginate gel-encapsulated fibroblasts, skeletal muscle cells kept proliferating without serum in the culture medium and differentiated further than were cultured in conditioned medium from the fibroblasts. Those results indicated that the secretome concurrently released from fibroblasts through the sealing hydrogel was effective as alternatives to serum or growth factors for promoting cell proliferation and differentiation in culture.
収録刊行物
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- 2019 IEEE 32nd International Conference on Micro Electro Mechanical Systems (MEMS)
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2019 IEEE 32nd International Conference on Micro Electro Mechanical Systems (MEMS) 599-600, 2019-01-01
IEEE