Effects of time-varying strong magnetic fields on Ca/sup 2+/ concentration in cultured bovine adrenal chromaffin cells
説明
We tested the effects of time-varying magnetic fields (from 0.07 to 1.7 T) on the transient elevation of intracellular Ca/sup 2+/ stimulated by bradykinin (BK) in bovine adrenal chromaffin cells. Addition of BK induced the transient increase in intracellular Ca/sup 2+/ within few minutes, and then decreased. The magnetic field delayed and perfectly suppressed the increase in the absence of external Ca/sup 2+/. The inhibitory effects were caused by exposure for only 15 minutes at 1.7 T of magnetic flux density. These results suggested that the magnetic field inhibits Ca/sup 2+/ release from intracellular Ca/sup 2+/ stores.
収録刊行物
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- Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)
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Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286) 6 3290-3293, 2002-11-28
IEEE