書誌事項
- タイトル別名
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- IV. Effects of ruthenium red on the co-operative nature of calcium-binding
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説明
Ruthenium red combines with isolated synaptosomes, resulting in strong inhibition of their Ca2+-binding. In isotonic saline media, however, the dye-induced inhibition of Ca2+-binding is significantly greater than that expected for the amount of bound dye and Hill's exponent of the Ca2+-binding decreases to 1 with an increase in the amount of the dye bound. On the other hand in isotonic mannitol-sucrose solution, inhibition of synaptosmal Ca2+-binding brought about by the dye is proportional to the amount of dye bound. Based on these results, the effects of the dye on the co-operative nature of synaptosomal Ca2+-binding is discussed.
収録刊行物
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- The Journal of Membrane Biology
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The Journal of Membrane Biology 26 345-356, 1976-12-01
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