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Description
Abstract The pedicellaria of some species of sea urchins contain toxic substances, which are capable of causing injury. In particular, the pedicellaria venoms of the sea urchin, Tripneustes gratilla and Toxopneustes pileolus, exert a variety of pharmacological actions Fujiwara , 1935; Endean , 1961; Mendes et al., 1963; Feigen et al., 1966; Alender , 1967). Recently, Kimura et al. (1975) found toxic substances in pedicellaria of Toxopneustes pileolus and reported that these substances caused a contraction of the isolated smooth muscle. In the present experiments, a pharmacological characterization of the contractile response of an extract from T. pileolus on the longitudinal muscle of the isolated guinea pig ileum was investigated.
Journal
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- Toxicon
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Toxicon 18 689-693, 1980-01-01
Elsevier BV
