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説明
K. Koike Worldwide, hepatitis B virus (HBV) and hepatitis C virus (HCV) infect hundreds of millions of people persistently and induce a spectrum of chronic liver diseases. Hence, they have an impact on society in a number of domains including medical, sociologic and economic. Hepatocellular carcinoma (HCC) has become the most frequent cause of death in individuals persistently infected with HBV or HCV. In particular, HCV has gained increasing attention because of its wide and deep penetration into the community, coupled with a very high incidence of HCC in the persistent infection. Once liver cirrhosis is established in hosts infected with HCV HCC develops at a yearly rate of 5 7% ‘. Knowledge on the mechanism by which HCC develops in chronic HCV infection is, therefore, urgently required for the prevention of HCC.
収録刊行物
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- Digestive and Liver Disease
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Digestive and Liver Disease 33 2-6, 2001-02-01
Elsevier BV