Studies on the microbial formation of sugar derivatives of D-pantothenic acid

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Abstract A new derivative of pantothenic acid was found in a reaction mixture of Sporobolomyces coralliformis IFO 1032 incubated in a medium containing maltose and D -pantothenic acid. This new compound was isolated from an incubation mixture by active charcoal, Amberlite CG-50, Sephadex G-10 and DEAE-cellulose column chromatography, and by paper chromatography. Then, the compound was characterized as 4′(2′)-O-(α- D -glucopyranosyl)- D -pantothenic acid by various analytical methods, including bioautography, paper chromatography and infrared and NMR spectroscopy.

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