Phosphorylation of the Heavy Chain of Skeletal Muscle Myosin by Casein Kinase II: Localization of the Phosphorylation Site to the Amino Terminus1

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While the heavy chain of rabbit skeletal muscle myosin is not phosphorylatable by casein kinase II, it turned out to be phosphorylatable after removal of all of the light chains. The phosphorylation site for the kinase was determined to be Ser-1 and/or Ser-2 at the amino terminus.

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