65. The correlation of migraine with EEG findings

Association between migraine and epilepsy is well known. However, few previous studies characterizedmigraine andEEGfindings. Thepurpose of this studywas to evaluate the correlation ofmigraine with EEG findings in the patients with/without epilepsy, and to discuss the pathophysiology of migraine with EEG abnormality. The subjects were 21 patients with migraine, divided into 16 patients without other neurological involvement (migraine group) and the other 5 patients complicated with epilepsy (epilepsy group). We compared clinical manifestations, EEG findings and locations of headache. Six (37.5%) of the 16 patients with migraine and all (100%) with epilepsy group showed EEG abnormalities. EEG demonstrated centrotemporal paroxysms in 4 (66.7%)withmigraine and 4 (80%) with epilepsy group. In 11 (68.8%) of the 16 patients with migraine and 4 (80%) of the 5 patientswith epilepsy group, headache was located at frontotemporal area. These results revealed clinical features inmigrainewere similar to those in epilepsy group. Furthermore, EEG demonstrated centrotemporal paroxysms in many patients of both groups. These results suggest that the presence of EEG abnormalities with migraine is not related to the underlying epileptogenic pathology. The pathophysiology of migraine with EEG abnormalities cannot be explained by the epileptic syndrome.