Microassembly of spheroids by thermoresponsive gel probe

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In this paper, manipulation of cell spheroids was conducted to construct 3D cell structures for tissue engineering applications. The spheroids were manipulated using thermoresposnive gel, and the cell viability was checked. The manipulated cells show more than 90 % viability. The results indicate that the spheroids can be assembled inside thermoresponsive polymer solution to construct 3D in vitro cell systems with keeping their live conditions.

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