Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts.

ABSTRACT It contains the data of drug targets (gene names), uniprot identifiers, secondary linked data sources (e.g., PharmGKB), market drug name, chembl identifier, and pubchem compound identifier obtained from DGIdb. Instructions: Data were cleaned and duplicates were removed. Data were all categorical features. Inspiration: This dataset uploaded to U-BRITE for "DRG_DEPOT" summer 2023 team project. It is used for constructing R2G dataset, which will map drugs to their drug targets (gene -> protein = drug target) Acknowledgements Freshour SL, Kiwala S, Cotto KC, Coffman AC, McMichael JF, Song JJ, Griffith M, Griffith OL, Wagner AH. Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts. Nucleic Acids Res. 2021 Jan 8;49(D1):D1144-D1151. doi: 10.1093/nar/gkaa1084. PMID: 33237278; PMCID: PMC7778926. https://www.dgidb.org/ U-BRITE last update date: 06/09/2023

{"references": ["Sharon L Freshour and others, Integration of the Drug\u2013Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts, Nucleic Acids Research, Volume 49, Issue D1, 8 January 2021, Pages D1144\u2013D1151, https://doi.org/10.1093/nar/gkaa1084"]}

U-BRITE location: /data/project/ubrite/drg-depot/DGIdb/