Relationship between Sedentary Behavior and All-cause Mortality in Japanese Chronic Hemodialysis Patients : A Prospective Cohort Study

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書誌事項

タイトル
Relationship between Sedentary Behavior and All-cause Mortality in Japanese Chronic Hemodialysis Patients : A Prospective Cohort Study
著者
菱井, 修平
著者別名
  • Hishii, Shuhei
  • ヒシイ, シュウヘイ
学位授与大学
香川大学
取得学位
博士（医学）
学位授与番号
甲第737号
学位授与年月日
2020-03-24

説明

We investigated the relationship between sedentary behavior and all-cause mortality in patients undergoing hemodialysis. A total of 71 patients (39 men, 32 women, aged 72.1±11.7 years) were enrolled in this longitudinal study. Their sedentary behavior was measured using a tri-accelerometer that provides relative values per daily wearing time. We classified the sedentary behavior time into 2 groups (under the median: short-sedentary behavior (SB) group; over the median: long-SB group) and compared the groups’ clinical parameters. We compared the groups’ survival rates by using Kaplan-Meier curves and the log-rank test, and we performed multivariate analyses by a Cox-proportional hazard model to evaluate the relationship between the sedentary behavior and the survival rate. Twenty patients (28.2%) died during the observation period. The survival rate of the short-SB group was significantly higher than that of the long-SB group. Sedentary behavior was thus an important factor for all-cause mortality even after adjusting for confounding factors by a Cox-proportional hazard model. Sedentary behavior is closely linked to all-cause mortality, especially total days and non-hemodialysis days, and reducing sedentary behavior may be beneficial to reduce the all-cause mortality of patients on chronic hemodialysis.

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