Comparing the performance of visual estimation and standard uptake value of F-18 fluorodeoxyglucose positron emission tomography/computed tomography for detecting malignancy in pancreatic tumors other than invasive ductal carcinoma
書誌事項
- タイトル
- Comparing the performance of visual estimation and standard uptake value of F-18 fluorodeoxyglucose positron emission tomography/computed tomography for detecting malignancy in pancreatic tumors other than invasive ductal carcinoma
- タイトル別名
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- FDG-PET/CTでの浸潤性膵管癌以外の膵腫瘍の悪性病変の検出能における視覚評価と標準摂取率での評価の比較検討
- 著者
- 音見, 暢一
- 著者別名
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- オトミ, ヨウイチ
- Otomi, Youichi
- 著者
- 大塚, 秀樹
- 著者別名
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- オオツカ, ヒデキ
- Otsuka, Hideki
- 著者
- テラザワ, カオリ
- 著者別名
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- Terazawa, Kaori
- 著者
- 能勢, 隼人
- 著者別名
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- ノセ, ハヤト
- Nose, Hayato
- 著者
- 久保, 典子
- 著者別名
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- クボ, ミチコ
- Kubo, Michiko
- 著者
- 松崎, 健司
- 著者別名
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- マツザキ, ケンジ
- Matsuzaki, Kenji
- 著者
- 生島, 仁史
- 著者別名
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- イクシマ, ヒトシ
- Ikushima, Hitoshi
- 著者
- 坂東, 良美
- 著者別名
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- バンドウ, ヨシミ
- Bando, Yoshimi
- 著者
- 原田, 雅史
- 著者別名
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- ハラダ, マサフミ
- Harada, Masafumi
- 学位授与大学
- 徳島大学
- 取得学位
- 博士（医学）
- 学位授与番号
- 甲医第1209号
- 学位授与年月日
- 2014-03-24
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説明
Introduction The utility of FDG PET/CT for the detection and evaluation of invasive ductal carcinoma has been widely reported, but a few studies have assessed the utility of FDG PET/CT to detect malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Purpose To compare the diagnostic performance of visual estimation with the semi-quantitative scores of FDG PET/CT for detecting malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Material and Methods Images of pathologically proven pancreatic lesions from 32 patients were retrospectively evaluated : 14 benign lesions, 7 borderline (low malignant) lesions, and 11 malignant lesions. The average scores from visual estimation by the two observers were compared to two semi-quantiative analyses of FDG uptake in the lesions, namely the maximum standardized uptake value (SUVmax) and mean standardized uptake value (SUVmean). Results Visual analysis value, SUVmax and SUVmean were 0.33±0.21, 1.8±0.7 and 1.5±0.7 for the benign lesions, 0.70±0.28, 5.0±2.6 and 3.1±1.7 for the borderline lesions, and 0.73±0.18, 4.7±2.5 and 3.2±1.6 for the malignant lesions, respectively. Receiver operating characteristic analysis revealed the areas under the curves for detecting non-benign (malignant or borderline) lesions through visual analysis, SUVmax, and SUVmean were 0.914, 0.954, and 0.875, respectively. Conclusion For a variety of pancreatic lesions other than invasive ductal carcinoma, visual analysis and semi-quantitative analyses all showed strong diagnostic performance. However, semi-quantitative analysis with SUVmax proved to be the most effective method for detecting non-benign pancreatic lesions.