A new combined index of SUVmax of lymph node in PET/CT by a weighting coefficient plus its maximum minor axis in CECT to evaluate occult lymph node metastasis in clinical N0 patients with tongue cancer

書誌事項

タイトル
A new combined index of SUVmax of lymph node in PET/CT by a weighting coefficient plus its maximum minor axis in CECT to evaluate occult lymph node metastasis in clinical N0 patients with tongue cancer
タイトル別名
  • リンパ節のPET/CTによるSUVmaxに重み付け係数を乗じてCECTの最大短径を加えた新しいcombined indexによる舌癌の臨床的N0症例の潜在的リンパ節転移の評価
  • Combined index to evaluate N0 neck
著者
金村, 亮
著者別名
  • カナムラ, リョウ
  • Kanamura, Ryo
著者
スズキ, モトユキ
著者別名
  • Suzuki, Motoyuki
著者
オトザイ, シンジ
著者別名
  • Otozai, Shinji
著者
ヨシイ, タダシ
著者別名
  • Yoshii, Tadashi
著者
オカモト, ヒデヒコ
著者別名
  • Okamoto, Hidehiko
著者
北村, 嘉章
著者別名
  • キタムラ, ヨシアキ
  • Kitamura, Yoshiaki
著者
阿部, 晃治
著者別名
  • アベ, コウジ
  • Abe, Koji
著者
フジイ, タカシ
著者別名
  • Fujii, Takashi
著者
武田, 憲昭
著者別名
  • タケダ, ノリアキ
  • Takeda, Noriaki
学位授与大学
徳島大学
取得学位
博士(医学)
学位授与番号
甲医第1491号
学位授与年月日
2021-03-17

説明

To predict occult nodal metastasis in clinical N0 patients with tongue cancer, we developed combined index (CI) : SUVmax of the largest lymph node in PET/CT by weighting coefficient plus its maximum minor axis (< 10 mm) in contrast-enhanced CT (CECT). In this retrospective study, 57 clinical N0 patients with tongue cancer, who underwent elective supraomohyoid neck dissection at cervical levels of I-III were enrolled. The cutoff value of SUVmax of 2.0 obtained using receiver operating characteristic (ROC) analysis predicted the postoperative positive cervical levels containing metastatic lymph nodes from clinical N0 cervical levels in tongue cancer patients with a sensitivity of 54.5% and a specificity of 78.2%. The cutoff value of CI with weighting coefficient of 1.5 obtained using ROC analysis was 9.8 at the maximum area under the curve of 0.750. The cutoff value of 9.8 predicted the postoperative positive cervical levels containing metastatic lymph nodes from clinical N0 cervical levels in tongue cancer patients with a sensitivity of 68.2% and a specificity of 81.5%. These findings suggest that CI of functional PET/CT and morphological CECT components might improve the diagnostic performance of occult nodal metastasis to select clinical N0 patients with tongue cancer preferable for elective neck dissection.

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