佐賀県肝疾息高罹患地区におけるHCV抗体陽性者の臨床的研究
メタデータ
- タイトル別名
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- Clinical Investigation of HCV Antibodies Positive Cases in the District with High Mortality Rate of Liver Desease at Saga Prefecture
- 公開日
- 1993-02-25
- 資源種別
- journal article
- 権利情報
-
- 本資料は権利関係や内容に配慮し、本文を非公開にしています。閲覧をご希望の場合は冊子体をご利用ください。
- Due to considerations regarding rights and content, the full text is not available for public access.. Please use the printed version.
- 『福岡医学雑誌』の利用について
- Regarding the Use of "Fukuoka Acta Medica"
- アクセス権
- 非共有・非公開
- 巻
- 84
- 号
- 2
- ページ
- 54-57
- 公開者
- 福岡医学会
- データ作成者 (e-Rad)
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- 原, 俊哉 (70274602)
- 瀬戸口, 洋一
- 山本, 匡介 (00117285)
- 尾崎, 岩太 (80214120)
- 和田, 郁子
- 福島, 範子
- 水田, 敏彦 (80253607)
- 梶原, 進
- 堺, 隆弘 (30010367)
説明
The mortarity and morbidity rates of chronic liver disease (CLD) have been extremely high for several years at Saga prefecture in Japan. Epidemiorogical studied revealed districts with high mortality rate of CLD (H-district). We measured C 100-3Ab and HCVCoreAb (CoreAb) in the H-district and observed high discrepancy between C100-3 and CoreAb. In order to examine pathogenesis of this discrepancy, we determined serum HCVRNA in these cases. The positive cases of HCV-Ab among 459 subjects were 33.6% (159). 59 subject were positive for both, 88 were only positive for CoreAb, 7 were only positive for C100-3Ab. Serum HCVRNA was detected in 92% (22/24) of both positive cases, in 67% (6/9) of only CoreAb positive cases, in 43% (3/7) of only C100-3Ab positive cases. These results suggested the cases positive for C-100-3 and CoreAb have chronic liver injury due to HCV infection, while the cases positive for only CoreAb involves healthy carrier or the memory state of HCV infection without liver injury.
収録刊行物
-
- 福岡醫學雜誌
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福岡醫學雜誌 84 (2), 54-57, 1993-02-25
福岡医学会
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詳細情報 詳細情報について
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- CRID
- 2120026415028055552
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- NII書誌ID
- AN00215478
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- HANDLE
- 2324/7329374
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- ISSN
- 0016254X
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- 本文言語コード
- ja
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- データソース種別
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- IRDB
