Identification of the relationship and its mechanism between cardiac arrest and underlying sarcopenia
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- Mitsuhiro Fukata
- Principal Investigator
- 九州大学
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- 赤星 朋比古
- Co-Investigator
- 九州大学
About this project
- Japan Grant Number
- JP17K11577
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding organization
- Japan Society for the Promotion of Science
- Project/Area Number
- 17K11577
- Research Category
- Grant-in-Aid for Scientific Research (C)
- Allocation Type
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- Multi-year Fund
- Review Section / Research Field
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- Biological Sciences > Medicine, Dentistry, and Pharmacy > Clinical surgery > Emergency medicine
- Research Institution
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- Kyushu University
- Project Period (FY)
- 2017-04-01 〜 2023-03-31
- Project Status
- Completed
- Budget Amount*help
- 4,680,000 Yen (Direct Cost: 3,600,000 Yen Indirect Cost: 1,080,000 Yen)
Research Abstract
In patients with non-traumatic cardiac arrest, the presence of sarcopenia, as estimated by skeletal muscle area, was significantly associated with survival at 24 hours. In patients with atrial fibrillation who underwent catheter ablation, pectoral muscle area/body surface area was associated with an increased rate of the recurrence of atrial fibrillation in women. Serum myokine was measured in patients with atrial fibrillation, and somatomedin C was significantly correlated with 5m walking speed, but age was considered a confounding factor; Myostatin was significantly associated with 5m walking speed after age correction and may be useful as a marker of sarcopenia in patients with cardiac disease.
Keywords
Details 詳細情報について
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- CRID
- 1040000781970041728
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- Text Lang
- ja
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- Data Source
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- KAKEN