Profiling microbiota of bronchial fluids in the elderly and its association with oral cavities

About this project

Japan Grant Number
JP17K12006
Funding Program
Grants-in-Aid for Scientific Research
Funding organization
Japan Society for the Promotion of Science
Project/Area Number
17K12006
Research Category
Grant-in-Aid for Scientific Research (C)
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Biological Sciences > Medicine, Dentistry, and Pharmacy > Dentistry > Social dentistry
Research Institution
  • Niigata University
Project Period (FY)
2017-04-01 〜 2022-03-31
Project Status
Completed
Budget Amount*help
4,550,000 Yen (Direct Cost: 3,500,000 Yen Indirect Cost: 1,050,000 Yen)

Research Abstract

The source of the bacteria involved in silent aspiration remains to be completely defined. The purpose of the present study was to obtain reliable evidence on silent aspiration of oral bacteria in elderly patients. Our results suggest that bacteria in bronchial fluids associated with silent aspiration are derived from saliva, and that the bronchial fluids of elderly patients with an impaired swallowing reflex may have a characteristic microbiota. In addition, our results suggest that oral hygiene is important to reduce silent aspiration and to subsequently prevent the occurrence of aspiration pneumonia in elderly patients.

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