Comprehensive evaluation of diffusion information using statistical model and pharmacokinetic analysisApplication to the head and neck
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- Toru Chikui
- Principal Investigator
- 九州大学
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- 川野 真太郎
- Co-Investigator
- 九州大学
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- 吉浦 一紀
- Co-Investigator
- 九州大学
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- 北本 江梨奈
- Co-Investigator
- 九州大学
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- 山下 泰生
- Co-Investigator
- 九州大学
About this project
- Japan Grant Number
- JP18K09770
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding organization
- Japan Society for the Promotion of Science
- Project/Area Number
- 18K09770
- Research Category
- Grant-in-Aid for Scientific Research (C)
- Allocation Type
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- Multi-year Fund
- Review Section / Research Field
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- Basic Section 57060:Surgical dentistry-related
- Research Institution
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- Kyushu University
- Project Period (FY)
- 2018-04-01 〜 2023-03-31
- Project Status
- Completed
- Budget Amount*help
- 4,030,000 Yen (Direct Cost: 3,100,000 Yen Indirect Cost: 930,000 Yen)
Research Abstract
In the analysis of diffusion-weighted images of the maxillofacial area, it was possible to clarify the characteristics of lesions in the maxillofacial area using the monoexponential model, IVIM model, and gamma distribution model. Parameters derived from the gamma distribution were considered to reflect pathology. In addition, it was found that there is a good correlation with the parameters of I V I M, and that there is a complementary relationship. From pharmacokinetic analysis based on dynamic imaging and model analysis of diffusion-weighted images, the ratio of cells and stroma correlated with diffusion in vivo. Correlation was found in parameters related to blood flow information, but the correlation coefficient was not very high. From this, it was considered necessary to consider the results of each of the two imaging methods as diagnostic criteria.
Keywords
Details 詳細情報について
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- CRID
- 1040000782001507968
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- Text Lang
- ja
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- Data Source
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- KAKEN
- IRDB