Estimation of Underlying Pathologies and Pursuit of Personalized Treatments for Central Nervous System Autoimmune Diseases Using Biomarkers

About This Project

Japan Grant Number
JP25K10629 (JGN)
Funding Program
Grants-in-Aid for Scientific Research
Funding Organization
Japan Society for the Promotion of Science

Kakenhi Information

Project/Area Number
25K10629
Research Category
Grant-in-Aid for Scientific Research (C)
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Basic Section 51030:Pathophysiologic neuroscience-related
Research Institution
  • Kyushu University
Project Period (FY)
2025-04-01 〜 2028-03-31
Project Status
Granted
Budget Amount*help
4,550,000 Yen (Direct Cost: 3,500,000 Yen Indirect Cost: 1,050,000 Yen)

Research Abstract

多発性硬化症(MS)、視神経脊髄炎スペクトラム障害(NMOSD)、MOG抗体関連疾患(MOGAD)といった中枢神経系自己免疫疾患のモデル動物や患者の脳脊髄液や血液などを用いて、体液性バイオマーカーを複合的に測定し、背景にある免疫病態や中枢神経病理の推定を目指す。そして背景病理を意識した治療が有用かを検証する。

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