Analysis of common molecular mechanisms associated with epithelium differentiation and hair growth

KAKEN

About This Project

Japan Grant Number
JP21K19578 (JGN)
Funding Program
Grants-in-Aid for Scientific Research
Funding Organization
Japan Society for the Promotion of Science

Kakenhi Information

Project/Area Number
21K19578
Research Category
Grant-in-Aid for Challenging Research (Exploratory)
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Research Institution
  • Saitama Medical University
Project Period (FY)
2021-07-09 〜 2023-03-31
Project Status
Completed
Budget Amount*help
6,370,000 Yen (Direct Cost: 4,900,000 Yen Indirect Cost: 1,470,000 Yen)

Research Abstract

本研究では、研究代表者である片桐らが樹立した転写共役因子Smad4のコンディショナルノックアウトマウスを用いて、発毛に関わる細胞内シグナルを解析する。Smad4 cKOマウスの上皮細胞を抽出し、Smad4 cKOによって変動する遺伝子群をRNA-seqで解析する。

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