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- 宍戸, 仙太郎
- 東北大学医学部泌尿器科
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- 渋谷, 正三
- 仙台社会保険病院
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- 佐々木, 桂一
- 八戸市立病院泌尿器科
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- 渋谷, 昌良
- 平鹿総合病院泌尿器科
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- 加藤, 弘彰
- 雄勝中央病院泌尿器科
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- 今林, 健一
- 東北大学医学部泌尿器科
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- 小津, 堅輔
- 公立気仙沼総合病院泌尿器科
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- 大沼, 徹太郎
- 古川市立病院泌尿器科
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- 海法, 裕男
- 東北労災病院泌尿器科
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- 菅原, 奎二
- 仙台社会保険病院泌尿器科
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- 中野, 正和
- 国立仙台病院泌尿器科
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- 山中, 雅夫
- 仙台鉄道病院泌尿器科
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- 新田, 貴一
- 長井市立病院泌尿器科
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- 松下, 鈆三郎
- 米沢市立病院泌尿器科
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- 斉藤, 克之
- 大原総合病院泌尿器科
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- 斉藤, 武志
- 寿泉堂総合病院泌尿器科
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- 宮田, 宏洋
- いわき共立病院泌尿器科
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- 竹内, 睦雄
- 福島労災病院泌尿器科
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- 千葉, 隆一
- 白河厚生総合病院泌尿器科
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- 黒沢, 昌也
- 静岡厚生病院泌尿器科
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- 塩, 暢夫
- 静岡済生会病院泌尿器科
書誌事項
- タイトル別名
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- A DOUBLE-BLIND COMPARISON OF THE EFFICACY OF CEFATRIZINE (S-640P) AND AMPICILLIN (AB-PC) IN URINARY TRACT INFECTION
- ニジュウ モウケンホウ ニヨル Cefatrizine S 640P ト Am
この論文をさがす
抄録
Cefatrizine (S-640P, 1g/day, p.o.) and ampicillin (AB-PC, 1g/day, p.o.) were administered to 150 cases of acute urinary tract infections, and the efficacy of these drugs was compared with double blind procedure. Except 5 drop-out cases (2 in S-640P, and 3 in AB-PC), which had not visited the hospital after first administration of the drugs, the background of 145 cases were analyzed according to 33 articles, and it was to be satisfied in its uniformity as the subject of this trial. The final evaluation of therapeutic effect of each drug was decided according to the individual evaluation of the effect on urinary microorganism, urinary findings, and general status of the patients, except the side-effect. These results were analyzed statistically, and no significant difference was observed between these evaluations. Furthermore, x2-test, Wilcoxon's procedure, and calculation of several coefficients of correlation were carried out, but any significant difference between the action of these drugs could not be observed. As the side-effect, blister formation on the mucous membrane (1), exanthema (3), diarrhea (2), and slight increase of s-GOT and Al-P-ase (1) were observed in S-640P group; blister formation on mouth lip (1), decrease of neutrophilic leucocyte and increase of lymphocyte (1), exanthema (1), and increase of s-GOT, s-GPT and Al-P-ase (1) were found in AB-PC group. But all of these were slight and temporary, and these needed neither suspension of drug administration nor some available therapies. The clinical efficacy of S-640P was 74.0% on the 4th day of administration and 72.6% on the 8th day of administration, while the efficacy of AB-PC was 69.0% on the 4th day and 76.6% on the 8th day of administration. With the results obtained above, it was concluded that S-640P and AB-PC should have almost the same therapeutic effect on the simple acute urinary tract infections.
収録刊行物
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- 泌尿器科紀要
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泌尿器科紀要 21 (7), 681-703, 1975-07
京都大学医学部泌尿器科学教室
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詳細情報 詳細情報について
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- CRID
- 1050282677154386560
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- NII論文ID
- 120002232963
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- NII書誌ID
- AN00208315
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- ISSN
- 00181994
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- HANDLE
- 2433/121842
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- NDL書誌ID
- 1683966
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- 本文言語コード
- ja
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- 資料種別
- departmental bulletin paper
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- データソース種別
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- IRDB
- NDL
- CiNii Articles