Retrovirus infection and retinoid
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Human T -cell leukemia virus type I (HTLV-I) is a human retrovirus and an etiologic agent of adult T-cell leukemia/lymphoma (ATL/ATLL). The subtypes acute and lymphoma have a poor prognosis with a median survival rate of approximately 6 months. Some excellent therapeutic strategies for ATL are required. In present study, we show effects of a new therapeutic agent, retinoid, for proliferation, CD25 expression, NFκ-B transcription activity, influence of thiol compound. Furthermore, we clarified a mechanism of retinoid for ATL cells. Finally, we showed an evaluation of retinoid therapy in clinical including for skin involvement.
Departmental Bulletin Paper
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収録刊行物
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- ACTA MEDICA KINKI UNIVERSITY
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ACTA MEDICA KINKI UNIVERSITY 34 (1), 1-13, 2009-06-01
The Kinki University Medical Association
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詳細情報 詳細情報について
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- CRID
- 1050282677516259584
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- NII論文ID
- 120005736760
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- ISSN
- 03866092
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- 本文言語コード
- en
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- 資料種別
- departmental bulletin paper
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- データソース種別
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- IRDB
- CiNii Articles
