A novel detection technique of polyamide binding sites by photo-induced electron transfer in (Br)U substituted DNA

HANDLE オープンアクセス
  • 木崎, 誠一朗
    Department of Science, Graduate School of Science, Kyoto University
  • 朝光, 世煌
    Department of Science, Graduate School of Science, Kyoto University
  • 橋谷, かおり
    Department of Science, Graduate School of Science, Kyoto University
  • 板東, 俊和
    Department of Science, Graduate School of Science, Kyoto University
  • 杉山, 弘
    Department of Science, Graduate School of Science, Kyoto University
  • T, Bando
    Department of Science, Graduate School of Science, Kyoto University
  • H, Sugiyama
    Department of Science, Graduate School of Science, Kyoto University・Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University

抄録

We report the photochemistry of (Br)U substituted DNA as a versatile platform to investigate the binding sites of pyrene conjugated pyrrole imidazole polyamides (PIPs). The results suggest that the approach can be used on a routine basis for the screening of polyamide binding sites.

収録刊行物

詳細情報 詳細情報について

  • CRID
    1050282810834197504
  • NII論文ID
    120006462491
  • ISSN
    13597345
  • HANDLE
    2433/230919
  • 本文言語コード
    en
  • 資料種別
    journal article
  • データソース種別
    • IRDB
    • CiNii Articles

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