1000 spider silkomes: Linking sequences to silk physical properties
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- 荒川, 和晴
- Institute for Advanced Biosciences, Keio University; Faculty of Environment and Information Studies, Keio University; Graduate School of Media and Governance, Keio University; Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences
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- 河野, 暢明
- Institute for Advanced Biosciences, Keio University; Graduate School of Media and Governance, Keio University
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- マライ, アリ・アンドレス
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science
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- 立石, 綾香
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science; Department of Material Chemistry, Kyoto University
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- 伊福, 菜穂
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science
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- 増永, 啓康
- Japan Synchrotron Radiation Research Institute
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- 佐藤, 良太
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science; Spiber Inc.
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- 土屋, 康佑
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science; Department of Material Chemistry, Kyoto University
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- 大利, 麟太郎
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science; Spiber Inc.
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- ペドラゾリ, ダニエル
- Spiber Inc.
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- 篠原, 麻夏
- Spiber Inc.
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- 伊藤, 雄介
- Spiber Inc.
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- 中村, 浩之
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science; Spiber Inc.
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- 谷川, 明男
- Graduate School of Agricultural and Life Sciences, University of Tokyo
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- 鈴木, 佑弥
- Graduate School of Life and Environmental Sciences, University of Tsukuba; The United Graduate School of Agricultural Sciences, Kagoshima University
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- Ichikawa, Takeaki
- Kokugakuin Kugayama High School
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- 藤田, 将平
- Graduate School of Agriculture, Saga University
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- 藤原, 正幸
- Institute for Advanced Biosciences, Keio University
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- 冨田, 勝
- Institute for Advanced Biosciences, Keio University; Faculty of Environment and Information Studies, Keio University; Graduate School of Media and Governance, Keio University
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- ブラミレス, シーン
- Evolution and Ecology Research Centre, University of New South Wales; Present address: NMR Facility, Mark Wainwright Analytical Centre, University of New South Wales
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- チュア, ジョアン
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science
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- クレイグ, ヘイミッシュ・キャメロン
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science; Evolution and Ecology Research Centre, University of New South Wales
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- フーン, チューン・ピン
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science; Department of Material Chemistry, Kyoto University
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- グレコ, ガブリエル
- Department of Civil, Environmental and Mechanical Engineering, University of Trento
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- グアン, ジュアン
- Beijing Advanced Innovation Center for Biomedical Engineering, School of Materials Science and Engineering, Beihang University
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- ホランド, クリス
- Natural Materials Group, Department of Materials Science and Engineering, The University of Sheffield
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- カプラン, デビッド・L
- Department of Biomedical Engineering, Tufts University
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- スーデッシュ, クマー
- School of Biological Sciences, Universiti Sains Malaysia
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- マンダル, ビマン・B
- Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG); Center for Nanotechnology, IITG; School of Health Sciences and Technology, IITG
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- Norma-Rashid, Y.
- Institute of Biological Sciences, Faculty of Science, University of Malaya
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- オクタビアニ, ヌル・アリア
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science
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- プレダ, ルクサンダ・C
- Department of Biomedical Engineering, Tufts University
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- プーニョ, 二コラ・M
- Department of Civil, Environmental and Mechanical Engineering, University of Trento; School of Engineering and Materials Science, Queen Mary University of London
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- ラジュコワ, ランガム
- Institute for Frontier Materials, Deakin University
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- ワン, シャオキン
- College of Textile and Clothing Engineering, Soochow University
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- 矢澤, 健二郎
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science
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- ツェン, チャオズ
- College of Textile and Clothing Engineering, Soochow University
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- 沼田, 圭司
- Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science; Department of Material Chemistry, Kyoto University
説明
Spider silks are among the toughest known materials and thus provide models for renewable, biodegradable, and sustainable biopolymers. However, the entirety of their diversity still remains elusive, and silks that exceed the performance limits of industrial fibers are constantly being found. We obtained transcriptome assemblies from 1098 species of spiders to comprehensively catalog silk gene sequences and measured the mechanical, thermal, structural, and hydration properties of the dragline silks of 446 species. The combination of these silk protein genotype-phenotype data revealed essential contributions of multicomponent structures with major ampullate spidroin 1 to 3 paralogs in high-performance dragline silks and numerous amino acid motifs contributing to each of the measured properties. We hope that our global sampling, comprehensive testing, integrated analysis, and open data will provide a solid starting point for future biomaterial designs.
収録刊行物
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- Science Advances
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Science Advances 8 (41), 2022-10
American Association for the Advancement of Science (AAAS)
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詳細情報 詳細情報について
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- CRID
- 1050293788308420480
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- ISSN
- 23752548
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- HANDLE
- 2433/276739
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- IRDB
- Crossref
- KAKEN
