- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Knowledge Graph Search feature is available on CiNii Labs
- Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
Bulky Bipyridine-Type Ligand-Enabled para-Selective C–H Borylation of Aromatic Compounds
-
- Enta, Taisei
- Department of Interdisciplinary Engineering Sciences, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University
-
- Yoshino, Genki
- Department of Interdisciplinary Engineering Sciences, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University
-
- Kuninobu, Yoichiro
- Institute for Materials Chemistry and Engineering, Kyushu University Department of Interdisciplinary Engineering Sciences, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University
Description
We successfully developed a para-selective C–H borylation of aromatic compounds using iridium catalysts with bulky bipyridine-type ligands. The key to success is the introduction of bulky substituents (m-terphenyl groups) at the 4- and 4′-positions of the bipyridine-type ligands to sterically protect both sides and back of the catalysts, thereby efficiently preventing substrate orientation that gives ortho- and meta-borylated products. Using these ligands, higher para-selectivity was achieved compared to the conventional iridium-catalyzed para-selective C–H borylation. Interestingly, high para-selectivity was achieved even when using aromatic compounds with small substituents such as ethyl or isopropyl groups on the aro-matic ring.
Journal
-
- ChemRxiv
-
ChemRxiv 2025-03-20
Cambridge University Press
- Tweet
Details 詳細情報について
-
- CRID
- 1050585407778261632
-
- ISSN
- 25732293
-
- HANDLE
- 2324/7347382
-
- Text Lang
- en
-
- Article Type
- journal article
-
- Data Source
-
- IRDB