NF-κB, inflammation, immunity and cancer: coming of age
書誌事項
- 公開日
- 2018-01-22
- 資源種別
- journal article
- 権利情報
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- http://www.springer.com/tdm
- DOI
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- 10.1038/nri.2017.142
- 公開者
- Springer Science and Business Media LLC
この論文をさがす
説明
Fourteen years have passed since nuclear factor-κB (NF-κB) was first shown to serve as a molecular lynchpin that links persistent infections and chronic inflammation to increased cancer risk. The young field of inflammation and cancer has now come of age, and inflammation has been recognized by the broad cancer research community as a hallmark and cause of cancer. Here, we discuss how the initial discovery of a role for NF-κB in linking inflammation and cancer led to an improved understanding of tumour-elicited inflammation and its effects on anticancer immunity.
収録刊行物
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- Nature Reviews Immunology
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Nature Reviews Immunology 18 (5), 309-324, 2018-01-22
Springer Science and Business Media LLC
