Effect of S-PRG Eluate on Biofilm Formation and Enzyme Activity of Oral Bacteria
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- Masahiro Yoneda
- Center for Oral Diseases, Fukuoka Dental College, 3-2-1 Hakataekimae, Hakata-ku 812-0011, Japan
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- Nao Suzuki
- Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan
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- Yosuke Masuo
- Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan
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- Akie Fujimoto
- Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan
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- Kosaku Iha
- Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan
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- Kazuhiko Yamada
- Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan
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- Tomoyuki Iwamoto
- Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan
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- Takao Hirofuji
- Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan
書誌事項
- 公開日
- 2012
- 資源種別
- journal article
- 権利情報
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- http://creativecommons.org/licenses/by/3.0/
- DOI
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- 10.1155/2012/814913
- 公開者
- Wiley
この論文をさがす
説明
<jats:p>Recently, the antibacterial activity of a composite resin containing prereacted glass ionomer (S-PRG) filler was revealed. We examined the effect of an S-PRG eluate on various biologic activities of<jats:italic>Streptococcus mutans</jats:italic>and<jats:italic>Porphyromonas gingivalis</jats:italic>. Adherence ability of<jats:italic>S. mutans</jats:italic>was evaluated by microtiter plate assay; protease and gelatinase activities of<jats:italic>P. gingivalis</jats:italic>were examined by synthetic substrate hydrolysis and gelatin film spot assay, respectively. Coaggregation of<jats:italic>P. gingivalis</jats:italic>with<jats:italic>Fusobacterium nucleatum</jats:italic>was also examined. S-PRG eluate was found to suppress streptococcal adherence. S-PRG eluate inhibited the protease and gelatinase activities of<jats:italic>P. gingivalis</jats:italic>and the coaggregation between<jats:italic>P. gingivalis</jats:italic>and<jats:italic>F. nucleatum</jats:italic>. These results indicate that S-PRG eluate suppresses streptococcal adherence and inhibits the protease and coaggregation activities of<jats:italic>P. gingivalis</jats:italic>. These findings may prompt research into novel strategies for preventing caries and periodontitis.</jats:p>
収録刊行物
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- International Journal of Dentistry
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International Journal of Dentistry 2012 1-6, 2012
Wiley
