Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue

  • Atsushi Tomokiyo
    Division of Endodontics, Kyushu University Hospital, Fukuoka, Japan
  • Shinichiro Yoshida
    Division of Endodontics, Kyushu University Hospital, Fukuoka, Japan
  • Sayuri Hamano
    Department of Endodontology and Operative Dentistry, Faculty of Dental Science, Kyushu University, Fukuoka, Japan
  • Daigaku Hasegawa
    Division of Endodontics, Kyushu University Hospital, Fukuoka, Japan
  • Hideki Sugii
    Division of Endodontics, Kyushu University Hospital, Fukuoka, Japan
  • Hidefumi Maeda
    Division of Endodontics, Kyushu University Hospital, Fukuoka, Japan

書誌事項

公開日
2018-08-26
資源種別
journal article
権利情報
  • http://creativecommons.org/licenses/by/4.0/
DOI
  • 10.1155/2018/5450768
公開者
Wiley

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説明

<jats:p>Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL also contains MSC population, and many researchers have isolated them and performed their detailed characterization. Here, we review the current understanding of the features and functions of MSC population in PDL tissues and discuss their possibility for the application of PDL regeneration.</jats:p>

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