Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility
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説明
We analyzed 1,900 Turkish Behçet's disease cases and 1,779 controls genotyped with the Immunochip. The most significantly associated SNP was rs1050502, a tag SNP for HLA-B*51. In the Turkish discovery set, we identified three new risk loci, IL1A-IL1B, IRF8, and CEBPB-PTPN1, with genome-wide significance (P5 × 10
収録刊行物
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- Nature Genetics
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Nature Genetics 49 (3), 438-443, 2017-02-06
Springer Science and Business Media LLC
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詳細情報 詳細情報について
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- CRID
- 1360009142734316032
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- DOI
- 10.1038/ng.3786
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- ISSN
- 15461718
- 10614036
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- PubMed
- 28166214
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- 資料種別
- journal article
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- データソース種別
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- Crossref
- KAKEN
- OpenAIRE
