2-Styrylchromone derivatives as potent and selective monoamine oxidase B inhibitors
書誌事項
- 公開日
- 2019-11
- 権利情報
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- https://www.elsevier.com/tdm/userlicense/1.0/
- https://www.elsevier.com/legal/tdmrep-license
- DOI
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- 10.1016/j.bioorg.2019.103285
- 公開者
- Elsevier BV
この論文をさがす
説明
A series of eighteen 2-styrylchromone derivatives (see Chart 1) were synthesized and evaluated for their monoamine oxidase (MAO) A and B inhibitory activities. Many of the derivatives inhibited MAO-B comparable to pargyline (a positive control), and most of them inhibited MAO-B selectively. Of the eighteen derivatives, compound 9 having methoxy group at R
収録刊行物
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- Bioorganic Chemistry
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Bioorganic Chemistry 92 103285-, 2019-11
Elsevier BV
