Animal Model To Study Klebsiella pneumoniae Gastrointestinal Colonization and Host-to-Host Transmission
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- Taylor M. Young
- Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
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- Andrew S. Bray
- Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
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- Ravinder K. Nagpal
- Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
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- David L. Caudell
- Department of Pathology-Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
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- Hariom Yadav
- Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
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- M. Ammar Zafar
- Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
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- Denise Monack
- editor
抄録
<jats:p> An important yet poorly understood facet of the life cycle of a successful pathogen is host-to-host transmission. Hospital-acquired infections (HAI) resulting from the transmission of drug-resistant pathogens affect hundreds of millions of patients worldwide. <jats:named-content content-type="genus-species">Klebsiella pneumoniae</jats:named-content> , a Gram-negative bacterium, is notorious for causing HAI, with many of these infections difficult to treat, as <jats:named-content content-type="genus-species">K. pneumoniae</jats:named-content> has become multidrug resistant. Epidemiological studies suggest that <jats:named-content content-type="genus-species">K. pneumoniae</jats:named-content> host-to-host transmission requires close contact and generally occurs through the fecal-oral route. </jats:p>
収録刊行物
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- Infection and Immunity
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Infection and Immunity 88 (11), e00071-, 2020-10-19
American Society for Microbiology