Buchwald–Hartwig Amination of Nitroarenes
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- Fumiyoshi Inoue
- Department of Material Chemistry Graduate School of Engineering Kyoto University Katsura, Nishikyo-ku Kyoto 615-8510 Japan
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- Myuto Kashihara
- Department of Material Chemistry Graduate School of Engineering Kyoto University Katsura, Nishikyo-ku Kyoto 615-8510 Japan
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- M. Ramu Yadav
- Department of Material Chemistry Graduate School of Engineering Kyoto University Katsura, Nishikyo-ku Kyoto 615-8510 Japan
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- Yoshiaki Nakao
- Department of Material Chemistry Graduate School of Engineering Kyoto University Katsura, Nishikyo-ku Kyoto 615-8510 Japan
説明
<jats:title>Abstract</jats:title><jats:p>The Buchwald–Hartwig amination of nitroarenes was achieved for the first time by using palladium catalysts bearing dialkyl(biaryl)phosphine ligands. These cross‐coupling reactions of nitroarenes with diarylamines, arylamines, and alkylamines afforded the corresponding substituted arylamines. A catalytic cycle involving the oxidative addition of the Ar−NO<jats:sub>2</jats:sub> bond to palladium(0) followed by nitrite/amine exchange is proposed based on a stoichiometric reaction.</jats:p>
収録刊行物
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- Angewandte Chemie International Edition
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Angewandte Chemie International Edition 56 (43), 13307-13309, 2017-09-22
Wiley
