Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin Aging

DOI Web Site 3 Citations 111 References Open Access
  • Tuba M. Ansary
    Department of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, Japan
  • Md. Razib Hossain
    Department of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, Japan
  • Koji Kamiya
    Department of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, Japan
  • Mayumi Komine
    Department of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, Japan
  • Mamitaro Ohtsuki
    Department of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, Japan

Description

<jats:p>Skin is the largest and most complex organ in the human body comprised of multiple layers with different types of cells. Different kinds of environmental stressors, for example, ultraviolet radiation (UVR), temperature, air pollutants, smoking, and diet, accelerate skin aging by stimulating inflammatory molecules. Skin aging caused by UVR is characterized by loss of elasticity, fine lines, wrinkles, reduced epidermal and dermal components, increased epidermal permeability, delayed wound healing, and approximately 90% of skin aging. These external factors can cause aging through reactive oxygen species (ROS)-mediated inflammation, as well as aged skin is a source of circulatory inflammatory molecules which accelerate skin aging and cause aging-related diseases. This review article focuses on the inflammatory pathways associated with UVR-mediated skin aging.</jats:p>

Journal

Citations (3)*help

See more

References(111)*help

See more

Related Projects

See more

Details 詳細情報について

Report a problem

Back to top