Hippocampal cAMP regulates HCN channel function on two time scales with differential effects on animal behavior
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- Kyle A. Lyman
- Department of Neurology, Northwestern University Feinberg School of Medicine, 303 E. Chicago Ave., Chicago, IL 60611, USA.
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- Ye Han
- Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, USA.
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- Chengwen Zhou
- Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, USA.
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- Isabelle Renteria
- Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, USA.
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- Gai-Linn Besing
- Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, USA.
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- Jonathan E. Kurz
- Department of Pediatrics, Northwestern University Feinberg School of Medicine, 225 E. Chicago Ave., Chicago, IL 60611, USA.
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- Dane M. Chetkovich
- Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, USA.
説明
<jats:p>cAMP-mediated effect on HCN channel surface trafficking and mouse behavior depends on activation time scale.</jats:p>
収録刊行物
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- Science Translational Medicine
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Science Translational Medicine 13 (621), 2021-11-24
American Association for the Advancement of Science (AAAS)