Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy
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- J.A. Obeso
- HM CINAC Hospital Universitario HM Puerta del Sur, Mostoles Madrid Spain
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- M. Stamelou
- Department of Neurology Philipps University Marburg Germany
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- C.G. Goetz
- Department of Neurological Sciences Rush University Medical Center Chicago Illinois USA
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- W. Poewe
- Department of Neurology Medical University Innsbruck Innsbruck Austria
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- A.E. Lang
- Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J Safra Program in Parkinson's Disease Toronto Western Hospital Toronto Canada
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- D. Weintraub
- Department of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA
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- D. Burn
- Medical Sciences Newcastle University Newcastle UK
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- G.M. Halliday
- Brain and Mind Centre, Sydney Medical School The University of Sydney Sydney Australia
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- E. Bezard
- Université de Bordeaux Institut des Maladies Neurodégénératives, Centre National de la Recherche Scientifique Unité Mixte de Recherche 5293, Institut des Maladies Neurodégénératives Bordeaux France
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- S. Przedborski
- Departments of Neurology, Pathology, and Cell Biology, the Center for Motor Neuron Biology and Disease Columbia University New York New York USA
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- S. Lehericy
- Institut du Cerveau et de la Moelle épinière – ICM, Centre de NeuroImagerie de Recherche – CENIR Sorbonne Universités UPMC Univ Paris 06, Inserm U1127, CNRS UMR 7225 Paris France
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- D.J. Brooks
- Clinical Sciences Department Newcastle University Newcastle UK
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- J.C. Rothwell
- Human Neurophysiology, Sobell Department UCL Institute of Neurology London UK
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- M. Hallett
- Human Motor Control Section, National Institute of Neurological Disorders and Stroke National Institutes of Health Bethesda Maryland USA
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- M.R. DeLong
- Department of Neurology Emory University School of Medicine Atlanta Georgia USA
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- C. Marras
- Morton and Gloria Shulman Movement Disorders Centre and the Edmond J Safra Program in Parkinson's disease, Toronto Western Hospital University of Toronto Toronto Canada
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- C.M. Tanner
- Movement Disorders and Neuromodulation Center, Department of Neurology University of California–San Francisco San Francisco California USA
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- G.W. Ross
- Veterans Affairs Pacific Islands Health Care System Honolulu Hawaii USA
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- J.W. Langston
- Parkinson's Institute Sunnyvale California USA
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- C. Klein
- Institute of Neurogenetics University of Luebeck Luebeck Germany
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- V. Bonifati
- Department of Clinical Genetics Erasmus University Medical Center Rotterdam The Netherlands
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- J. Jankovic
- Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology Baylor College of Medicine Houston Texas USA
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- A.M. Lozano
- Department of Neurosurgery Toronto Western Hospital University of Toronto Toronto Canada
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- G. Deuschl
- Department of Neurology, Universitätsklinikum Schleswig‐Holstein Christian Albrechts University Kiel Kiel Germany
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- H. Bergman
- Department of Medical Neurobiology Institute of Medical Research Israel‐Canada Jerusalem Israel
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- E. Tolosa
- Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clínic de Neurociències Hospital Clínic de Barcelona Barcelona Spain
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- M. Rodriguez‐Violante
- Movement Disorders Clinic Clinical Neurodegenerative Research Unit Mexico City Mexico
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- S. Fahn
- Department of Neurology Columbia University Medical Center New York New York USA
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- R.B. Postuma
- Department of Neurology, McGill University Montreal General Hospital Montreal Quebec Canada
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- D. Berg
- Klinik für Neurologie, UKSH, Campus Kiel Christian‐Albrechts‐Universität Kiel Germany
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- K. Marek
- Institute for Neurodegenerative Disorders New Haven Connecticut USA
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- D.G. Standaert
- Department of Neurology University of Alabama at Birmingham Birmingham Alabama USA
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- D.J. Surmeier
- Department of Physiology, Feinberg School of Medicine Northwestern University Chicago Illinois USA
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- C.W. Olanow
- Departments of Neurology and Neuroscience Mount Sinai School of Medicine New York New York USA
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- J.H. Kordower
- Research Center for Brain Repair Rush University Medical Center Chicago Illinois USA
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- P. Calabresi
- Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia University of Perugia Perugia Italy
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- A.H.V. Schapira
- University Department of Clinical Neurosciences, UCL Institute of Neurology University College London London UK
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- A.J. Stoessl
- Pacific Parkinson's Research Centre, Division of Neurology & Djavadf Mowafaghian Centre for Brain Health University of British Columbia British Columbia Canada
説明
<jats:title>ABSTRACT</jats:title><jats:p>This article reviews and summarizes 200 years of Parkinson's disease. It comprises a relevant history of Dr. James Parkinson's himself and what he described accurately and what he missed from today's perspective. Parkinson's disease today is understood as a multietiological condition with uncertain etiopathogenesis. Many advances have occurred regarding pathophysiology and symptomatic treatments, but critically important issues are still pending resolution. Among the latter, the need to modify disease progression is undoubtedly a priority. In sum, this multiple‐author article, prepared to commemorate the bicentenary of the shaking palsy, provides a historical state‐of‐the‐art account of what has been achieved, the current situation, and how to progress toward resolving Parkinson's disease. © 2017 International Parkinson and Movement Disorder Society</jats:p>
収録刊行物
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- Movement Disorders
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Movement Disorders 32 (9), 1264-1310, 2017-09
Wiley
