G-tail telomere HPA: simple measurement of human single-stranded telomeric overhangs
説明
Accurate measurement of telomeric 3'-overhang (G-tail) lengths is essential for investigation of the biological effects of telomere dysfunction. G-tail telomere hybridization protection assay (Gt-telomere HPA) has the advantages of being simple to perform, accurate and highly sensitive for G tails as short as 20 nucleotides. Furthermore, Gt-telomere HPA is specific and quantitative for human G tails, and can be used to assay cell lysates as well as genomic DNA.
収録刊行物
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- Nature Methods
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Nature Methods 2 (11), 829-831, 2005-10-21
Springer Science and Business Media LLC
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詳細情報 詳細情報について
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- CRID
- 1360574095041720832
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- NII論文ID
- 80017743878
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- DOI
- 10.1038/nmeth797
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- ISSN
- 15487105
- 15487091
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- PubMed
- 16278652
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