Palladium-Catalyzed Unimolecular Fragment Coupling of N-Allylamides Bearing a Tethered Nucleophile with the Translocation of an Amide Group

  • Mamoru Tobisu
    Department of Applied Chemistry, Graduate School of Engineering, Osaka University
  • Ryoma Shimazumi
    Department of Applied Chemistry, Graduate School of Engineering, Osaka University
  • Takuya Kodama
    Department of Applied Chemistry, Graduate School of Engineering, Osaka University

書誌事項

公開日
2023-01-30
資源種別
journal article
DOI
  • 10.1055/a-2022-1905
公開者
Georg Thieme Verlag KG

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説明

<jats:title>Abstract</jats:title> <jats:p>The palladium-catalyzed reaction of N-allylamides bearing a tethered nucleophile results in the extrusion of an amide moiety in the form of an isocyanate, with its subsequent capture by the pendant nucleophile­. This reaction involves the net catalytic transposition of an amide group.</jats:p>

収録刊行物

  • Synthesis

    Synthesis 56 (01), 134-142, 2023-01-30

    Georg Thieme Verlag KG

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