Diagnostic performance of peripheral leukocyte telomere G‐tail length for detecting breast cancer

DOI Web Site Web Site Web Site 2 Citations 25 References
  • Yumiko Koi
    Surgical Oncology Division of Radiation Biology and Medicine Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Yasuhiro Tsutani
    Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
  • Yukie Nishiyama
    Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Miyuki Kanda
    Collaborative Laboratory of Liquid Biopsy Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Yoshitomo Shiroma
    Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Yuki Yamamoto
    Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Shinsuke Sasada
    Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
  • Tomoyuki Akita
    Department of Epidemiology Infectious Disease Control and Prevention Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Norio Masumoto
    Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
  • Takayuki Kadoya
    Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
  • Ryou‐u Takahashi
    Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Junko Tanaka
    Department of Epidemiology Infectious Disease Control and Prevention Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
  • Morihito Okada
    Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
  • Hidetoshi Tahara
    Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan

Search this article

Description

<jats:title>Abstract</jats:title><jats:p>The telomere G‐tail (G‐tail) plays an essential role in maintaining chromosome stability. In this study, we assessed the leukocyte G‐tail length of breast cancer (BC) patients and cancer‐free individuals and evaluated the association between the G‐tail length and the presence of BC. A significant shortening of the median G‐tail length was observed in BC patients compared with cancer‐free individuals and was found in the early phase of BC. Our study indicated that the leukocyte G‐tail length might be a potential biomarker for BC detection.</jats:p>

Journal

Citations (2)*help

See more

References(25)*help

See more

Related Projects

See more

Keywords

Report a problem

Back to top