-
- Cynthia M. Solek
- Montreal Neurological Institute McGill University Montreal Quebec Canada
-
- Nasr Farooqi
- Montreal Neurological Institute McGill University Montreal Quebec Canada
-
- Myriam Verly
- Montreal Neurological Institute McGill University Montreal Quebec Canada
-
- Tony K. Lim
- Montreal Neurological Institute McGill University Montreal Quebec Canada
-
- Edward S. Ruthazer
- Montreal Neurological Institute McGill University Montreal Quebec Canada
説明
<jats:p>Converging lines of evidence from basic science and clinical studies suggest a relationship between maternal immune activation (MIA) and neurodevelopmental disorders such as autism spectrum disorder (ASD) and schizophrenia. The mechanisms through which MIA increases the risk of neurodevelopmental disorders have become a subject of intensive research. This review aims to describe how dysregulation of microglial function and immune mechanisms may link MIA and neurodevelopmental pathologies. We also summarize the current evidence in animal models of MIA. <jats:italic>Developmental Dynamics 247:588–619, 2018</jats:italic>. © 2017 Wiley Periodicals, Inc.</jats:p>
収録刊行物
-
- Developmental Dynamics
-
Developmental Dynamics 247 (4), 588-619, 2017-12-23
Wiley
