Rotavirus NSP1 Contributes to Intestinal Viral Replication, Pathogenesis, and Transmission

  • Gaopeng Hou
    Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA
  • Qiru Zeng
    Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA
  • Jelle Matthijnssens
    KU Leuven-University of Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Leuven, Belgium
  • Harry B. Greenberg
    VA Palo Alto Health Care System, Department of Veterans Affairs, Palo Alto, California, USA
  • Siyuan Ding
    Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA

抄録

<jats:p> Rotavirus remains one of the most important causes of severe diarrhea and dehydration in young children worldwide. Although NSP1 is dispensable for rotavirus replication in cell culture, its exact role in virus infection <jats:italic>in vivo</jats:italic> remains unclear. </jats:p>

収録刊行物

  • mBio

    mBio 12 (6), 2021-12-21

    American Society for Microbiology

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